From: Mutations of complement lectin pathway genes MBL2 and MASP2 associated with placental malaria
All | Placental malaria | No placental malaria | P-value | |
---|---|---|---|---|
Number of subjects | 269 | 145 | 124 | |
Mean age, years (± SD) | 21.45 (± 3.51) | 21.00 (± 3.17) | 21.98 (± 3.82) | 0.0511 |
Mean maternal hemoglobin, g/l (± SD) | 112.6 (± 1.82) | 106.3 (± 1.76) | 120.0 (± 1.61) | < 0.0011 |
Mean birth weight, grams (± SD) | 2760 (± 485) | 2698 (± 485) | 2833 (± 478) | 0.0232 |
Mean gestational age, weeks (± SD) | 38.11 (± 2.50) | 38.07 (± 2.77) | 38.16 (± 2.17) | 0.811 |
Proportion with | ||||
> 3 antenatal care visits | 0.49 | 0.44 | 0.55 | 0.0833 |
maternal anaemia (Hb < 11 g/dL) | 0.41 | 0.55 | 0.24 | < 0.0013 |
low birth weight (< 2500 g) | 0.25 | 0.30 | 0.20 | 0.0913 |
preterm delivery (< 37 weeks) | 0.25 | 0.27 | 0.23 | 0.483 |
Placental blood samples | ||||
PCR positive (P. falciparum) | 0.66 | 0.95 | 0.32 | < 0.0013 |
Microscopy positive (P. falciparum) | 0.48 | 0.88 | 0.00 | < 0.0013 |
Haemozin pigments present | 0.43 | 0.80 | 0.00 | < 0.0013 |