Table 2 Relationship between age and level of total IgG, IgG subclasses, and IgM responses to MSP3, MSP1-19, and GLURP
Antigens | Age groups (in years) | N | GM*IgG(95%CI) | GM*IgG1(95%CI) | GM*IgG2(95%CI) | GM*IgG3(95%CI) | GM*IgG4(95%CI) | GM*IgGM(95%CI) |
|---|---|---|---|---|---|---|---|---|
MSP3 | [0.5-3] | 79 | 2.96 (2.88-3.04) | 0.18 (0.14-0.23) | 0.23 (0.21-0.24) | 0.29 (0.22-0.37) | 0.05 (0.04-0.06) | 1.16 (1.06-1.28) |
] 3-5] | 69 | 3.22 (3.13-3.31) | 0.24 (0.19-0.31) | 0.22 (0.19-0.26) | 0.49 (0.38-0.64) | 0.05 (0.04-0.06) | 0.99 (0.88-1.18) | |
] 5-10] | 84 | 3.35 (3.25-3.45) | 0.41 (0.33-0.52) | 0.28 (0.25-0.30) | 0.71 (0.56-0.92) | 0.06 (0.05-0.07) | 1.21 (1.06-1.39) | |
> 10 | 21 | 3.51 (3.30-3.70) | 0.69 (0.40-1.21) | 0.35 (0.26-0.47) | 1.05 (0.63-1.75) | 0.14 (0.03-0.54) | 1.39 (1.12-1.73) | |
P | 0,01 | 0,01 | 0,01 | 0,01 | 0,002 | 0,10 | ||
MSP1-19 | ] 0.5-3] | 79 | 3.13 (0.99-3.28) | 1.19 (0.97-1.45) | 0.21 (0.18-0.23) | 0.40 (0.33-0.48) | 0.02 (0.01-0.03) | 0.86 (0.77-0.96) |
] 3-5] | 69 | 3.07 (2.95-3.19) | 0.97 (0.80-1.17 | 0.26 (0.24-0.29) | 0.48 (0.40-0.57) | 0.03 (0.02-0.05) | 1.22 (1.11-1.35) | |
] 5-10] | 84 | 3.21 (3.07-3.34) | 1.02 (0.86-1.21) | 0.30 (0.27-0.34) | 0.64 (0.54-0.75) | 0,03 (0,03-0,09) | 1.41 (1.29-1.54) | |
> 10 | 21 | 3.09 (2.89-3.31) | 1.33 (0.96-1.86) | 0.35 (0.27-0.45) | 0.52 (0.37-0.74) | 0.03 (0.02-0.05) | 0.98 (0.77-1.25) | |
P | 0,072 | 0.01 | 0.001 | 0.001 | 0.09 | 0.01 | ||
GLURP | ] 0.5-3] | 79 | 3.13 (3.02-3.25) | 0.62 (0.51-0.76) | 0.29 (0.26-0.32) | 0.44 (0.38-0.50) | 0.03 (0.01-0.06) | 0.54 (0.45-0.65) |
] 3-5] | 69 | 3.41 (3.28-3.55) | 0.77 (0.63-0.94) | 0.36 (0.32-0.41) | 0.55 (0.48-0.63) | 0.01 (0.01-0.02) | 0.80 (0.72-0.88) | |
] 5-10] | 84 | 3.68 (3.53-3.84) | 0.84 (0.69-1.09) | 0.51 (0.43-0.61) | 0.60 (0.52-0.68) | 0.05 (0.02-0.09) | 0.95 (0.84-1.09) | |
> 10 | 21 | 3.89 (3.58-4.22) | 1.35 (0.96-1.88) | 0.64 (0.51-0.82) | 0.88 (0.66-1.17) | 0.05 (0.02-0.09) | 2.00 (1.47-2.73) | |
P | 0.01 | 0.01 | 0.01 | 0.01 | 0.056 | 0.01 |