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Table 2 Descriptive statistics of diagnostic performance for severe malaria

From: Predictive value of lymphocytopenia and the neutrophil-lymphocyte count ratio for severe imported malaria

Parameter

Cut-off value

Sensitivity

Specificity

PPV

NPV

Youden’s

AUROC

Total leukocyte count

≥ 6.5 Ă— 109/L

0.59 (0.46-0.71)

0.75 (0.71-0.80)

0.28 (0.21-0.37)

0.92 (0.88-0.95)

0.34

0.70 (0.63-0.78)

Neutrophil count

≥ 3.4 Ă— 109/L

0.64 (0.51-0.76)

0.56 (0.51-0.61)

0.19 (0.14-0.25)

0.91 (0.86-0.94)

0.2

0.61 (0.53-0.69)

Lymphocyte count

< 0.7 Ă— 10 9 /L

0.33 (0.22-0.46)

0.72 (0.67-0.76)

0.16 (0.10-0.24)

0.87 (0.83-0.90)

0.05

0.51 (0.43-0.59)

NLCR

≥ 2.8

0.77 (0.64-0.86)

0.44 (0.39-0.49)

0.18 (0.14-0.24)

0.92 (0.87-0.96)

0.21

0.57 (0.50-0.64)

CRP

>141 mg/L

0.80 (0.67-0.89)

0.76 (0.71-0.80)

0.33 (0.25-0.42)

0.96 (0.93-0.98)

0.56

0.84 (0.79-0.89)