Skip to main content

Table 1 Demographic and clinical data for study population $

From: Systemic release of high mobility group box 1 (HMGB1) protein is associated with severe and fatal Plasmodium falciparum malaria

Characteristic

UM(n = 33)

SM(n = 70)

p value

Pooled samples

p value

Non-fatal(n = 82)

Fatal(n = 21)

Age (years)

3.0 (1.7-6.75)

1.9 (1.0-3.3)

0.0065

2.25 (1.2-4.4)

2.05 (1.2-3.55)

0.86

Weight (kg)

13.0 (10.0 -21.0)

10.5 (8.5-13.0)

0.0044

11.0 (9.0-15.0)

11.5 (10.0-13.0)

0.71

Female (%)

14 (42.4)

37 (52.1)

0.4

37 (45.1)

14 (63.6)

0.15

Days unwell prior to presentation

3 (2–4)

3 (3–4)

0.32

3 (3–4)

3.5 (2–6.5)

0.87

Parasitaemia (parasites/uL)

3.9 × 104 (6.1 × 103-1.4 × 105)

4.0 × 104 (9.2 × 103-1.7 × 105)

0.59

3.8 × 104 (6.3 × 103-1.4 × 105)

1.2 × 105 (1.4 × 103-3.6 × 105)

0.074

  1. UM = uncomplicated malaria, SM = severe malaria (includes cerebral malaria (CM; n = 32), severe malarial anaemia (SMA; n = 35), CM/SMA (n = 1), non-CM/SMA (n = 3)).
  2. $All variables are presented as median (interquartile range) unless otherwise indicated. Groups were compared using Mann Whitney U or Fisher exact test.