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Table 3 Sensitivity, specificity, positive predictive value and negative predictive value of the HRP2 and pan pLDH-based test ( Plasmodium falciparum gametocytaemia was considered negative for P. falciparum )

From: Field evaluation of HRP2 and pan pLDH-based immunochromatographic assay in therapeutic monitoring of uncomplicated falciparum malaria in Myanmar

Day Sensitivity (95% CI) Specificity (95% CI) Positive predictive value Negative predictive value
HRP2 pLDH HRP2 pLDH HRP2 pLDH HRP2 pLDH
D0 100 100 NR2 NR2 100 100 NR3 NR3
(95.3–100%) (95.3–100%)    (95.3–100%) (95.3–100%)   
D3 100 50 0 73.97 5.19 9.52 NR3 96.43
(39.7–100%) (6.8–93.2%) (0.0–4.9%) (62.4–83.6%) (1.4–12.8%) (1.2–30.4%)   (87.7–99.6%)
D7 NR1 NR1 1.32 85.53 0 0 100 100
   (0.1–7.1%) (75.6–92.6%) (0–4.8%) (0–28.5%) (2.5–100%) (94.5–100%)
D14 NR1 NR1 9.33 93.33 0 0 100 100
   (3.8–18.3%) (85.1–97.8%) (0–5.3%) (0–52.2%) (59.0–100%) (94.9–100%)
D21 100 100 27.40 93.06 3.64 37.50 100 100
(15.8–100%) (29.2–100%) (17.6–39.1%) (84.5–97.7%) (0.4–12.5%) (8.5–75.5%) (83.2–100%) (94.6–100%)
D28 100 88.89 39.44 96.87 4.44 80 100 98.41
(15.8–100%) (51.8–99.7%) (29.0–51.8%) (89.2–99.6%) (0.5–15.2%) (44.4–97.5%) (87.7–100%) (91.5–99.9%)
  1. NR = Not relevant.
  2. 1 Sensitivity was not calculated because of no true positive.
  3. 2 Specificity was not calculated because of no true negative.
  4. 3 NPV was not calculated because of no true negative.