Figure 1

Schematic representation of Plasmodium CPW-WPC family proteins. (A) Diagram showing the common structure shared between CPW-WPC family proteins. Each protein contains a signal peptide and 5 repeated CPW-WPC domains, each having 4–6 cysteine residues. (B) ClustalW alignment of the first 2 CPW-WPC domains showing conserved amino acids (asterisks) and the arrangement of cysteines (highlight). Note that the WxC pattern is typically located at the end of each domain (box).