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Figure 5 | Malaria Journal

Figure 5

From: Mechanisms of protective immune responses induced by the Plasmodium falciparum circumsporozoite protein-based, self-assembling protein nanoparticle vaccine

Figure 5

SAPN have continuous and delayed processing through the early endosome of dendritic cells. Confocal microscopy images taken at either ten minutes (Panels A, B) or twenty-four hours (Panels C, D) following co-culture of bone marrow-derived dendritic cells and either ovalbumin (Panels A, C) or Pf CSP-SAPN (Panels B, D). Red is labeled Ova or SAPN; green is labeled EE, TAP or lysosomal protein; yellow is the result of merged images of red labeled Ova or SAPN and the green organelle marker dye; blue is the DAPI nuclear stain. Representative images shown; six independent experiments.

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Malaria Journal

ISSN: 1475-2875

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