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Figure 6 | Malaria Journal

Figure 6

From: Mechanisms of protective immune responses induced by the Plasmodium falciparum circumsporozoite protein-based, self-assembling protein nanoparticle vaccine

Figure 6

SAPN have delayed organelle fusion and interaction with lysosomal enzymes. TEM images after twenty-four hours co-culture of bone marrow-derived dendritic cells and gold-labeled Pf CSP-SAPN (Panel A), ovalbumin (Panel B), or colloidal gold particles alone (Panel C). White arrows indicate clusters of gold-encapsulated SAPN; black arrows indicate areas containing a high-density of lysosomal enzymes. 20–67 × magnifications shown. Representative images shown; six independent experiments.

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Malaria Journal

ISSN: 1475-2875

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