Figure 3
Representative ECG changes induced by Plasmodium berghei ANKA infection. ECG traces (A, B) and power spectra curves (C, D) from one uninfected (left) and one ECM mouse (right) on day 6 of infection. Note the global lengthening of ECG intervals in ECM mouse (B). In power spectral graphs, the total power of all the spectral components is represented by the area under the entire curve and is presented in units of square milliseconds/Hz. Area under peaks present between specific frequency bands provides information about low frequency (LF), and high frequency (HF) rhythms embedded within the HR pattern. LF lower bound is 0.03; LF upper bound is 1.5; HF lower bound is 1.51; and HF upper bound is 5.0. In C, uninfected mouse, total power is 0.64 ms2, LF power is 0.23 ms2, HF power is 0.26 ms2, and LF/HF ratio is 0.85 ms2. In D, ECM mouse, total power is 34,419.22 ms2, LF power is 33,774.93 ms2, HF power is 571.44 ms2, and LF/HF ratio is 59.1 ms2.