Table 1 Chromatographic parameters for β-artemether and lumefantrine at different mobile phase compositions using Halo RP-Amide stationary phase column
Mobile phase composition; Acetonitrile: 1mM phosphate buffer pH 3.0 | β-artemether retention factor (k’) | β-artemether peak symmetry factor (As) | Lumefantrine retention factor (k’) | Lumefantrine peak symmetry factor (As) |
|---|---|---|---|---|
54:46 | 5.5 | 1.0 | 1.5 | 1.4 |
52:48 | 6.8 | 1.0 | 2.0 | 1.3 |
50:50 | 7.5 | 1.0 | 2.8 | 1.8 |