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Table 2 Genotype frequencies of the kdr , ace-1 locus and mean level of NSE, MFO and GST activity in Anopheles gambiae s.s. Kisumu and M’Bé

From: Insecticide resistance status of Anopheles gambiae s.s population from M’Bé: a WHOPES-labelled experimental hut station, 10 years after the political crisis in Côte d’Ivoire

 

Kisumu

M’Bé

F(kdr-w)

-

0.33 (226)

F(kdr-e)

-

0.00 (226)

F(ace-1R)

-

0.00 (226)

α-Na

0.086 ±0.007 a (40)

0.155 ±0.012 b (40)

β-Na

0.084 ±0.007a (40)

0.125 ±0.017b (40)

MFO

0.095 ±0.008 a (38)

0.198 ±0.020 b (36)

GST

0.295 ±0.032a (40)

0.378 ±0.085a (40)

  1. α-Na: NSE activity with substrate alpha-naphthyl acetate (μmol α-naphthol produced/min/mg protein).
  2. β-Na: NSE level with substrate beta-naphthyl acetate (μmol β-naphthol produced/min/mg protein).
  3. MFO: MFO level (nmol equivalent unit of cytochrome P450/mg protein).
  4. GST: GST level (nmol GSH conjugated/min/mg protein).
  5. (): Number tested of Anopheles gambiae s.s. females.
  6. Different letter superscripts indicates enzyme level significantly higher than with the Kisumu susceptible An. gambiae s.s. strain (P < 0.05).
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Malaria Journal

ISSN: 1475-2875

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