TY - JOUR AU - Chaccour, Carlos J. AU - Kobylinski, Kevin C. AU - Bassat, Quique AU - Bousema, Teun AU - Drakeley, Chris AU - Alonso, Pedro AU - Foy, Brian D. PY - 2013 DA - 2013/05/07 TI - Ivermectin to reduce malaria transmission: a research agenda for a promising new tool for elimination JO - Malaria Journal SP - 153 VL - 12 IS - 1 AB - The heterogeneity of malaria transmission makes widespread elimination a difficult goal to achieve. Most of the current vector control measures insufficiently target outdoor transmission. Also, insecticide resistance threatens to diminish the efficacy of the most prevalent measures, indoor residual spray and insecticide treated nets. Innovative approaches are needed. The use of endectocides, such as ivermectin, could be an important new addition to the toolbox of anti-malarial measures. Ivermectin effectively targets outdoor transmission, has a novel mechanism of action that could circumvent resistance and might be distributed over the channels already in place for the control of onchocerciasis and lymphatic filariasis. SN - 1475-2875 UR - https://doi.org/10.1186/1475-2875-12-153 DO - 10.1186/1475-2875-12-153 ID - Chaccour2013 ER -