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Figure 1 | Malaria Journal

Figure 1

From: Cloning and characterization of bifunctional enzyme farnesyl diphosphate/geranylgeranyl diphosphate synthase from Plasmodium falciparum

Figure 1

Schematic diagram of the isoprenoid biosynthesis and downstream products in Plasmodium falciparum . Bisphosphonates are known to inhibit FPPS/GGPPS, thereby preventing the synthesis of FPP and GGPP required for the biosynthesis of ubiquinone, dolichol, carotenoids, menaquinone, tocopherol, and protein prenylation. MEP: methyl erythritol phosphate.

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Malaria Journal

ISSN: 1475-2875

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