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Table 1 Apparent kinetic constants for Plasmodium falciparum FPPS,(rPfFPPS)

From: Cloning and characterization of bifunctional enzyme farnesyl diphosphate/geranylgeranyl diphosphate synthase from Plasmodium falciparum

Varied substrate Fixed substrate K M (μM) V max (nmol/min/mg)
DMAPP (0–150 μM) IPP 50 μM 68 ± 5 452.5 ± 16
GPP (0–50 μM) IPP 50 μM 7.8 ± 1.3 341 ± 19
FPP (0–50 μM) IPP 50 μM 2.06 ± 0.4 326.5 ± 16
IPP (0–80 μM) DMAPP 100 μM 2 ± 0.3 169 ± 5.4
IPP (0–80 μM) GPP 40 μM 0.81 ± 0.1 224 ± 3.4
IPP (0–50 μM) FPP 50 μM 2.4 ± 0.3 155.6 ± 4
  1. Concentration ranges for each varied substrate are indicated. Activity versus varied substrate concentration plots are depicted on Additional file 4.