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Table 2 Diagnostic performances of the Care startand VIKIA Malaria Ag Pf/Pantest (reading time: 30 minutes) for the detection of P. falciparum and non-falciparum species in Lyon and Bamako

From: Evaluation of the malaria rapid diagnostic test VIKIA malaria Ag Pf/Pan™ in endemic and non-endemic settings

 

Care Start Malaria™

VIKIA Malaria Ag Pf/Pan™

 

Pf or mixed

non-Pf

Pf or mixed

non-Pf

Lyon

    

Sensitivity % (95% CI)

  

98.0

60.0

  

(87.8–99.9)

(32.9–82.5)

Specificity % (95% CI)

  

93.1

100.0

  

(85.8–96.9)

(96.6–100.0)

PPV % (95% CI)

  

87.3

100.0

  

(74.9–94.3)

(62.9–100.0)

NPV % (95% CI)

  

98.9

95.7

  

(93.4–99.9)

(90.6–98.3)

Bamako

    

Sensitivity % (95% CI)

96.2

60.0

94.6

100

(90.8–98.6)

(17.0–92.7)

(88.8–97.6)

(46.3–100.0)

Specificity % (95% CI)

97.7

99.4

98.0

99.2

(96.0–98.7)

(98.5–99.8)

(96.4–98.9)

(98.1–99.7)

PPV % (95% CI)

89.9

42.9

91.1

45.5

(83.4–94.2)

(11.8–79.8)

(84.7–95.1)

(18.1–75.4)

NPV % (95% CI)

99.1

99.7

98.8

100.0

(97.9–99.7)

(98.9–100.0)

(97.5–99.5)

(99.3–100.0)

  1. PPV positive predictive value, NPV negative predictive value, Pf P. falciparum, non-Pf Plasmodium non-falciparum.