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Table 2 Evolution of the prevalence of Pfdhfr point mutations in codons 16, 51, 59, 108, and 164

From: Population genetics analysis during the elimination process of Plasmodium falciparum in Djibouti

 

51

59

108

  

N (Asn) (W)

I (Ile) (M)

C (Cys) (W)

R (Arg) (M)

S (Ser) (W)

N (Asn) (M)

Year

N

AAT

ATT

TGT

CGT

AGC

AAC

1998

36

100

0

97.2

2.8

97.2

2.8

1999

50

96.0

4.0

94.0

6.0

92.0

8.0

2002

4

100

0

100

0

100

0

2009

13

NA

NA

0

100

0

100

  1. Proportions (%) of single nucleotide polymorphism are presented: Pfdhfr Plasmodium falciparum dihydrofolate reductase, N, number of samples with at least a result at one codon; W wild-type, M mutant. NA; no results detected. Codons 16 and 164 showed only wild-type codons in all years studied.