Skip to main content

Table 2 Evolution of the prevalence of Pfdhfr point mutations in codons 16, 51, 59, 108, and 164

From: Population genetics analysis during the elimination process of Plasmodium falciparum in Djibouti

  51 59 108
   N (Asn) (W) I (Ile) (M) C (Cys) (W) R (Arg) (M) S (Ser) (W) N (Asn) (M)
Year N AAT ATT TGT CGT AGC AAC
1998 36 100 0 97.2 2.8 97.2 2.8
1999 50 96.0 4.0 94.0 6.0 92.0 8.0
2002 4 100 0 100 0 100 0
2009 13 NA NA 0 100 0 100
  1. Proportions (%) of single nucleotide polymorphism are presented: Pfdhfr Plasmodium falciparum dihydrofolate reductase, N, number of samples with at least a result at one codon; W wild-type, M mutant. NA; no results detected. Codons 16 and 164 showed only wild-type codons in all years studied.