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Table 3 Recovery data for artemether and lumefantrine from laboratory prepared formulations of Coartem ®

From: Determination of artemether and lumefantrine in anti-malarial fixed-dose combination tablets by microemulsion electrokinetic chromatography with short-end injection procedure

 

Exp. No.

% of the target concentration

Added amount (mg)

Found amount (mg)

Recovery (%)

Mean recovery ± RSD (%)

Artemether

      
 

1

 

7.60

7.73

101.7

 
 

2

80

7.87

7.65

97.2

100.8 ± 3.2

 

3

 

8.21

8.48

103.3

 
 

1

 

9.97

9.78

98.1

 
 

2

100

10.23

10.75

104.2

100.5 ± 3.3

 

3

 

10.52

10.42

99.0

 
 

1

 

11.86

11.91

100.4

 
 

2

120

12.25

12.43

101.5

100.3 ± 1.2

 

3

 

12.72

12.59

99.0

 

Lumefantrine

      
 

1

 

7.55

7.64

101.2

 
 

2

80

7.77

7.77

100.0

99.8 ± 1.4

 

3

 

7.85

7.72

98.3

 
 

1

 

10.16

10.28

101.2

 
 

2

100

10.19

10.01

98.2

99.3 ± 1.7

 

3

 

10.73

10.55

98.3

 
 

1

 

11.75

11.48

97.7

 
 

2

120

11.93

11.85

99.3

98.8 ± 0.9

 

3

 

12.38

12.30

99.4