Skip to main content
Figure 3 | Malaria Journal

Figure 3

From: Host immune constraints on malaria transmission: insights from population biology of within-host parasites

Figure 3

Efficiency of mature gametocytes production versus host exposure to asexual forms if gametocytes unaffected by acquired immunity. Both immature and mature gametocytes are unaffected by the host’s acquired immunity. The simulations were binned by the logarithms of the parasite-days of intracellular asexual forms, PD Asx ; see text for definition. The horizontal bars show the bin width.(A) Fraction of simulations making mature gametocytes F MG versus PD Asx for simulated P. falciparum infections. (B) Same as (A), except for simulated P. vivax infections. (C) Logarithmic average of mature gametocyte parasite-days PD MG versus PD Asx for those simulated P. falciparum infections in which mature gametocytes are produced. Vertical bars are the standard deviation in the logarithmic average. (D) Same as (C) except for simulated P. vivax infections. (E) Color code for the host immunity-gamteocyte models. “Parasite Cleared”: host cleared all parasite forms within three years after primary release of merozoites from the liver. “Host Died”: host died of anemia within three years of primary release. Note: for each of two immune classes and host fates color coded, results are shown only for bins which contained 10 or more simulations.

Back to article page