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Table 1 Mixture decomposition (AMA-1)

From: Measurement of Plasmodium falciparum transmission intensity using serological cohort data from Indonesian schoolchildren

 i

 Titre range

      πi

      φi

       θi

1

-∞ < t < 10

0 (by definition)

0 (by definition)

0.247 (CI: 0.219 - 0.276)

2

10 < t < 40

3.06E-5 (CI: 1.67E-8 – 5.52E-3)

8.52E-4 (CI: 7.25E-7 – 0.0755)

0.382 (CI: 0.349 – 0.414)

3

40 < t < 70

8.26E-5 (CI: 5.59E-8 – 0.0108)

1.02E-3 (CI: 1.17E-6 – 0.0621)

1.68E-1 (CI: 1.44E-1 – 0.194)

4

70 < t < 100

2.21E-4 (CI: 2.12E-7 – 0.0208)

9.88E-4 (CI: 1.58E-6 – 0.0415)

0.0600 (CI: 0.0454 – 0.0772)

5

100 < t < 130

6.03E-4 (CI: 8.08E-7 – 0.0390)

1.59E-3 (CI: 3.70E-6 – 0.0444)

0.0356 (CI: 0.0245 – 0.0495)

6

130 < t < 160

1.63E-3 (CI: 3.01E-6 – 0.0706)

3.18E-3 (CI: 1.05E-5 – 0.0593)

0.0263 (CI: 0.0170 –0.0383)

7

160 < t < 190

4.38E-3 (CI: 1.17E-5 – 0.125)

5.92E-3 (CI: 3.02E-5 – 0.0741)

0.0182 (CI: 0.0107 – 0.0285)

8

190 < t < 228

0.0115 (CI: 5.003E-5 – 0.209)

9.77E-3 (CI: 7.91E-5 – 0.0831)

0.0113 (CI: 5.61E-3 – 0.0198)

9

228 < t < 258

0.0300 (CI: 1.97E-4 – 0.332)

0.0281 (CI: 3.87E-4 – 0.156)

0.0124 (CI: 6.43E-3–0.0213)

10

258 < t < 541

0.0748 (CI: 8.63E-4 – 0.485)

0.0657 (CI: 1.70E-3 – 0.244)

0.0113 (CI: 5.57E-3 – 0.0198)

11

541 < t < 710

0.174 (CI: 3.68E-3 – 0.644)

0.163 (CI: 0.0100 – 0.418)

0.0112 (CI: 5.60E-3 – 0.0197)

12

710 < t < 1547

0.352 (CI: 0.0156 – 0.801)

0.384 (CI: 0.0838 – 0.794)

0.0113 (CI: 5.60E-3 – 0.0198)

13

1547 < t < 1730

0.577 (CI: 0.0415 – 0.942)

0.161 (CI: 0.0187 – 0.818)

1.95E-3 (CI: 2.88E-4 – 6.45E-3)

  1. Medians and Bayesian Credible Intervals (CI, 2.5th to 97.5th percentile) of the estimated seroprevalence πi in each titre range i and the probabilities φi and θi that a seropositive or -negative person, respectively, has an AMA-1 titre in range i. The overall seroprevalence π was 0.0169 (CI: 6.24E-4 – 0.0888). The titres of 40 unexposed individuals living in Yogyakarta served as negative control group.