Skip to main content
Figure 3 | Malaria Journal

Figure 3

From: CYP450 phenotyping and metabolite identification of quinine by accurate mass UPLC-MS analysis: a possible metabolic link to blackwater fever

Figure 3

Time/Concentration-dependent oxidative stress produced in normal human erythrocytes by microsomal metabolites of quinine in vitro. Plotted are the changes in relative fluorescence units (RFU) for various quinine concentrations as a function of time A.) without human liver microsomes (HLM) and B.) with HLM. C.) Concentration dependence of ROS generation at 60 min is plotted. Each point represents values mean ± SD of four observations.

Back to article page

Malaria Journal

ISSN: 1475-2875

Contact us