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Figure 4 | Malaria Journal

Figure 4

From: CYP450 phenotyping and metabolite identification of quinine by accurate mass UPLC-MS analysis: a possible metabolic link to blackwater fever

Figure 4

Summary of quinine metabolism. Shown are the identified metabolites of quinine and their predicted redox active forms. The CYPs responsible for each transformation are indicated for each pathway and the CYPs primarily responsible for each transformation are indicated in green. Several other metabolites are listed for which the structures are not shown (3-hydroxyquinine, 6-hydroxyquinine, N-oxide, and multiply hydroxylated).

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