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Table 3 Signs and symptoms on admission in probable severe malaria patients (n= 393)

From: Severe malaria in Battambang Referral Hospital, an area of multidrug resistance in Western-Cambodia: a retrospective analysis of cases from 2006–2009

Sign/symptoms Total Died OR (95% CI) p-value*
n (%) n (%)
Fever 372 (95) 50 (13) 0.5 (0.2, 1.4) 0.19
Headache 247 (63) 32 (13) 0.8 (0.4, 1.4) 0.46
Dark urine 220 (56) 24 (11) 0.6 (0.3, 1.0) 0.06
Chills 207 (53) 26 (13) 0.8 (0.4, 1.4) 0.47
Impaired 166 (42) 23 (14) 1.0 (0.6, 1.8) 1
consciousness
(excl coma)
Abdominal pain 133 (34) 15 (11) 0.7 (0.4, 1.3) 0.29
Vomiting 104 (26) 10 (10) 0.6 (0.3, 1.2) 0.14
Anorexia 77 (20) 6 (8) 0.5 (0.2, 1.1) 0.1
Fatigue 75 (19) 8 (11) 0.7 (0.3, 1.5) 0.46
Coma 65 (17) 23 (35) 5.0 (2.7, 9.4) 0
Dyspnea 59 (15) 14 (24) 2.2 (1.1, 4.4) 0.03
Pallor 50 (13) 19 (38) 5.2 (2.7, 10.2) 0
GI Bleeding 41 (10) 4 (10) 0.6 (0.2, 1.9) 0.63
Dizziness 35 (9) 4 (11) 0.8 (0.3, 2.3) 0.8
Bleeding 26 (7) 5 (19) 1.5 (0.5, 4.2) 0.39
Nausea 25 (6) 4 (16) 1.2 (0.4, 3.6) 0.77
Jaundice 24 (6) 4 (17) 1.2 (0.4, 3.8) 0.76
Sweating 24 (6) 6 (25) 2.2 (0.8, 5.8) 0.13
Convulsion 20 (5) 5 (25) 2.2 (0.8, 6.2) 0.18
Confusion 11 (3) 0 (0) - -
Neck stiffness 2 (1) 1 (50) 6.2 (0.4, 101) 0.26
  1. *Fisher's Exact Test (2-sided).
  2. Adjusted for Dark Urine, Coma, Dyspnea and Pallor and Age Group, aOR (95% CI) of Dark Urine= 0.4 (0.2, 0.8), aOR of Coma = 5.8 (2.9, 11.5), aOR of Dyspnea = 2.5 (1.2, 5.4), aOR of Pallor = 4.2 (1.9, 9.0) and aOR of Age > 15 = 2.0 (0.9, 4.1).