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Table 5 Clinical course and complications experienced during hospital admission in probable severe malaria patients (n=393)

From: Severe malaria in Battambang Referral Hospital, an area of multidrug resistance in Western-Cambodia: a retrospective analysis of cases from 2006–2009

  Neg Pf Pv Pf+Pv Not recorded Total Died OR (95% CI) p-value*
    n    n (%) n (%)   
Prostration 82 150 16 5 12 265 (68) 53 (20) 15.6 (3.7, 65.2) 0
Impaired consciousness 81 143 14 5 11 254 (65) 53 (21) 18.1 (4.3, 75.4) 0
Respiratory distress 55 105 12 5 9 186 (48) 39 (21) 3.9 (2.0, 7.5) 0
Severe anaemia 55 90 11 3 10 169 (55) 27 (16) 1.1 (0.6, 2.1) 0.75
Hyperparasitaemia 1 101 7 11 8 128 (33) 13 (10) 0.6 (0.3, 1.1) 0.12
Jaundice 21 38 4 1 4 68 (17) 14 (21) 1.7 (0.9, 3.5) 0.12
Abdominal bleeding 23 29 5 0 5 62 (16) 12 (19) 1.6 (0.8, 3.2) 0.23
Frequent vomiting 17 34 6 3 1 61 (16) 5 (8) 0.5 (0.2, 1.3) 0.23
Circulatory collapse 17 32 7 1 3 60 (15) 43 (72) 67.5 (30.2, 150.8) 0**
Renal failure 8 16 2 0 1 27 (7) 16 (59) 16.8 (7.1, 39.7) 0**
Multiple convulsion 7 11 2 2 2 24 (6) 7 (29) 2.8 (1.1, 7.1) 0.03
Macroscopic 6 6 0 0 0 12 (3) 3 (25) 2.5 (0.7, 9.7) 0.17
haemoglobinuria
Hypoglycemia 1 7 0 2 0 10 (7) 3 (30) 1.5 (3.6, 6.2) 0.7
Pulmonary oedema 2 2 1 0 0 5 (2) 4 (80) 42.3 (4.5, 398) 0
  1. *Fisher's Exact Test (2-sided).
  2. **Adjusted for age group, circulatory collapse and renal failure, aOR (95% CI) of circulatory collapse=67.5 (23.2, 196) and aOR of renal failure=19.7 (4.6, 83.9).