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Table 1 Frequency of polymorphisms in the pvdhfr, pvmrp1, pvmdr1 and pvdhps genes for sensitive and resistant in vitro samples

From: In vitro chloroquine resistance for Plasmodium vivax isolates from the Western Brazilian Amazon

Gene/Polymorphisms

Sensitive samples

Resistant samples

p-value

Pvdhfr

   

58

7/10 (70%)

8/9 (88.9%)

0.313

117

8/10 (80%)

8/9 (88.9%)

0.596

173

1/10 (10%)

0/9 (0%)

0.330

pvmrp1

   

1282

9/9 (100%)

7/7 (100%)

NS

1393

9/9 (100%)

7/7 (100%)

NS

1419

4/9 (44.4%)

2/7 (28.6%)

0.515

1478

10/10 (100%)

9/9 (100%)

NS

1586

2/10 (20%)

2/9 (22.2%)

0.906

pvmdr1

   

908

1/10 (10%)

1/9 (11.1%)

0.937

958

10/10 (100%)

8/9 (8.9%)

0.279

Pvdhps

   

205

10/10 (100%)

9/9 (100%)

NS

382

5/8 (62.5%)

1/9 (11.1%)

0.027

383

0/8 (0%)

1/9 (11.1%)

0.331

  1. NS not significant.