Prognostic indicators in adults hospitalized with falciparum malaria in Western Thailand

Malaria Journal

Table 1 Clinical variables included in the ten sets, used in the logistic regression analyses

Variable	Bed side	Bedside and simple lab	WHO 1990	WHO 2000	Adapted AQ	Adapted AQ plus late stages	BCAM	RCAM	MSA	MPI
Seizures before admission	X	X	X	X	-	-	-	-	-	-
Clinical anaemia	X	X	-	-	-	-	-	-	-	-
Clinical jaundice	X	X	X	X	-	-	-	-	-	-
Bleeding	-	-	X	X	-	-	-	-	-	-
Blackwater fever	-	-	X	X	-	-	-	-	-	-
Temperature	X	X	X	-	-	-	-	-	-	-
Pulse	X	X	-	-	-	-	-	-	-	-
Respiratory rate	X	X	-	X	-	-	-	X	-	-
Respiratory distress, requiring mechanical ventilation	-	-	-	-	-	-	-	-	X	-
Liver palpable	X	X	-	-	-	-	-	-	-	-
GCS Total	X	X	X	X	X	X	X	X	X	X
Pulmonary oedema	-	-	X	X	-	-	-	-	-	-

X = included, - = not included.
BCAM score uses serum bicarbonate as a marker of acidosis with cut-off values of ≥24 mmol/L (score = 0) for normal, ≥15- < 24 mmol/L (score = 1) for deranged, and <15 mmol/L (score = 2) for very deranged along with thresholds for coma of GCS ≤14 and GCS ≤10 [23]. The acidosis and coma scores were summed to give the BCAM score, ranging from 0–4.
RCAM score uses respiratory rate as a surrogate marker for acidosis with cut offs of <20 breaths/min (score = 0) for normal, 20–39 breaths/min (score = 1) for deranged, and ≥40 breaths/min (score = 2) for very deranged.
The MSA score was defined as sum of 1 (severe anaemia [haemoglobin, <5 g/dL]) + 2 (acute renal failure [serum creatinine, >3 mg/dL or 250 μmol/L]) + 3 (respiratory distress, requiring mechanical ventilation) + 4 (cerebral malaria [GCS <11]), in which each variable was scored as 0 or 1, depending on its absence or presence, respectively [22].

ISSN: 1475-2875