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Table 9 Anti-malarial dr ug treatment and outcome

From: Prognostic indicators in adults hospitalized with falciparum malaria in Western Thailand

Variable

All

Alive

Died

 

+/−

%

+/−

%

+/−

%

Non-artemisinin/artemisinin derivative therapy

580/378

60.5

521/362

59.0

59/16

78.7

Parenteral quinine/artemisinin derivative. Patients given both parenteral quinine and artemisinin derivatives excluded

430/276

60.9

371/261

58.7

59/15

79.7

Oral quinine/artemisinin derivative and no parenteral anti-malarial

93/60

60.8

93/60

60.8

0/0

-

Number given/not given antibiotic a

124/818

13.2

94/778

10.8

30/40

42.9

No. given/not given inotrope

65/872

6.9

13/856

1.5

52/16

76.5

No. given/not given anti-epileptic drug

97/843

10.3

59/812

6.8

38/31

55.1

No. given/not given nasogastric tube

65/859

7.0

36/828

4.2

29/31

48.3

No. given/not given urinary catheter

207/728

22.1

142/725

16.4

65/3

95.6

No. given/not given blood transfusion

160/828

16.2

132/779

14.5

28/49

36.4

No. given/not given dialysis

31/898

3.3

7/854

0.8

24/44

77.4

No. given/not given ventilation

85/845

9.1

25/839

2.9

60/6

90.9

No. given/not given central venous access line

99/840

10.5

45/825

5.2

54/15

78.3

No. given/not given lumbar puncture

90/849

9.6

56/813

6.4

34/36

48.6

No. developing/not developing pulmonary oedema

14/958

1.4

7/888

0.8

7/70

9.1

No. developing/not developing oliguria

94/843

10.0

43/826

5.0

51/17

75.0

No. developing/not developing seizures

39/909

4.1

20/852

2.3

19/57

25.0

No. of nights in hospitalb

4 (1–34)

-

4 (1–34)

-

2 (1–27)

-

Coma Recovery Time/hb

24 (1–188)

-

-

-

-

-

Time to death/hb

-

-

-

-

44 (2–641)

-

  1. a excluding doxycycline and tetracycline given for malaria. b Median (range). All comparisons between alive and dead were statistically significant (P < 0.001, adjusted for study site).