Skip to main content
Figure 3 | Malaria Journal

Figure 3

From: Biological evaluation of hydroxynaphthoquinones as anti-malarials

Figure 3

Proposed mechanism of action of N3. P. falciparum 3D7 was loaded with Mitotracker Red CMXROS and ∆ΨMit measured after 1-hour incubations at the indicated concentrations using flow cytometry. a) Effects of compounds (dashed lines) compared to untreated controls (solid lines): CCCP 5 μM; N3 100 μM and Atovaquone 100 μM. b) Dose responses of different concentrations of solvent control, atovaquone and N3 in the inhibition of ∆ΨMit. (*) indicates a statistically significant difference from control values (P < 0.05), data were compared using one-way ANOVA and Dunnett’s post test.

Back to article page