Figure 5
Observed mefloquine plasma concentration after administration of a 2 × 125 = 250 mg (children) and 3 × 500 = 1500 mg (adults) dose in 63 Cambodian patients. The solid lines represent the mean population prediction the dotted lines the 95% prediction intervals. Triangles represent residual plasma concentrations of mefloquine or piperaquine found prior treatment initiation.