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Table 2 Baseline demographic and clinical parameters

From: Artesunate versus quinine in the treatment of severe imported malaria: comparative analysis of adverse events focussing on delayed haemolysis

Treatment group

All

Patients in whom delayed haemolysis could be assessed

 

All

All

Quinine (iv)

Quinine (iv) and artesunate (ir)

Artesunate (iv)

n

36

16

8

4

4

Female

13 (36)

4 (25)

2 (25)

1 (25)

1 (25)

Visiting friends and relatives

10 (28)

5 (31)

3 (38)

1 (25)

1 (25)

Traveling from sub-Saharan Africa

35 (97)

16 (100)

8 (100)

4 (100)

4 (100)

ICU treatment

25 (69)

12 (75)

6 (75)

4 (100)

2 (50)

Deaths

1 (3)

0 (0)

0 (0)

1 (25)

0 (0)

Hospital stay duration in days, median (IQR)

10 (7–18)

17 (9–30)

19 (11–30)

17 (4–46)

11 (6–16)

Age in years, median (IQR)

49 (35–55)

48 (37–57)

42 (35–48)

55 (41–59)

54 (28–62)

Temperature in °C

38.1 (37.5-38.6)

38.1 (37.6 – 38.6)

38.2 (37.4- 39.0)

37.1 (37.0 – 37.2)

38.5 (37.6 – 39.4)

Parasitaemia in%, median (IQR)

15 (7–25)

15 (7–24)

12 (5–15)

33 (26–39)

17 (8,-21)

Hb (g/dl, normal range:12.0-16.0 )

11.4 (10.2-12.5)

11.4 (10.0 – 12.9)

11.9 (9.4-14.3)

9.8 (6.4-13.1)

12.3 (7.7-16.9)

WBC (1000/μl, normal range: 3.5 – 10.5)

6.9 (5.4-8.4)

8.1 (5.3-10.9)

7.8 (4.6-11.0)

11.6 (0.0-24.8)

5.5 (1.1-9.9)

Creatinine (mg/dl, normal range: 0.6 – 1.3)

1.6 (1.0-2.2)

2.0 (1.3-2.8)

2.0 (0.7-3.3)

1.7 (0.0-3.6)

2.5 (0.6-4.4)

Bilirubin (mg/dl, normal range: <1.2)

4.0 (2.7-5.2)

5.0 (3.9-6.1)

4.9 (3.0-6.8)

4.2 (0.0-10.3)

5.9 (3.3-8.5)

GOT (U/l, normal range: <50)

115 (71–158)

153 (102–205)

149 (46–251)

163 (21–305)

153 (55–251)

GPT (U/l, normal range: <50)

75 (52–98)

84 (57–111)

77 (40–115)

65 (8–120)

116 (4–228)

C-Reactive Protein (mg/l, normal range:<5)

182 (145–219)

178 (130–226)

187 (90–284)

178 (25–331)

163 (74–225)

  1. Data are shown as number (%) or mean (with 95% standard deviation), if not indicated otherwise.