Treatment group | All | Patients in whom delayed haemolysis could be assessed | |||
---|---|---|---|---|---|
All | All | Quinine (iv) | Quinine (iv) and artesunate (ir) | Artesunate (iv) | |
n | 36 | 16 | 8 | 4 | 4 |
Female | 13 (36) | 4 (25) | 2 (25) | 1 (25) | 1 (25) |
Visiting friends and relatives | 10 (28) | 5 (31) | 3 (38) | 1 (25) | 1 (25) |
Traveling from sub-Saharan Africa | 35 (97) | 16 (100) | 8 (100) | 4 (100) | 4 (100) |
ICU treatment | 25 (69) | 12 (75) | 6 (75) | 4 (100) | 2 (50) |
Deaths | 1 (3) | 0 (0) | 0 (0) | 1 (25) | 0 (0) |
Hospital stay duration in days, median (IQR) | 10 (7–18) | 17 (9–30) | 19 (11–30) | 17 (4–46) | 11 (6–16) |
Age in years, median (IQR) | 49 (35–55) | 48 (37–57) | 42 (35–48) | 55 (41–59) | 54 (28–62) |
Temperature in °C | 38.1 (37.5-38.6) | 38.1 (37.6 – 38.6) | 38.2 (37.4- 39.0) | 37.1 (37.0 – 37.2) | 38.5 (37.6 – 39.4) |
Parasitaemia in%, median (IQR) | 15 (7–25) | 15 (7–24) | 12 (5–15) | 33 (26–39) | 17 (8,-21) |
Hb (g/dl, normal range:12.0-16.0 ) | 11.4 (10.2-12.5) | 11.4 (10.0 – 12.9) | 11.9 (9.4-14.3) | 9.8 (6.4-13.1) | 12.3 (7.7-16.9) |
WBC (1000/μl, normal range: 3.5 – 10.5) | 6.9 (5.4-8.4) | 8.1 (5.3-10.9) | 7.8 (4.6-11.0) | 11.6 (0.0-24.8) | 5.5 (1.1-9.9) |
Creatinine (mg/dl, normal range: 0.6 – 1.3) | 1.6 (1.0-2.2) | 2.0 (1.3-2.8) | 2.0 (0.7-3.3) | 1.7 (0.0-3.6) | 2.5 (0.6-4.4) |
Bilirubin (mg/dl, normal range: <1.2) | 4.0 (2.7-5.2) | 5.0 (3.9-6.1) | 4.9 (3.0-6.8) | 4.2 (0.0-10.3) | 5.9 (3.3-8.5) |
GOT (U/l, normal range: <50) | 115 (71–158) | 153 (102–205) | 149 (46–251) | 163 (21–305) | 153 (55–251) |
GPT (U/l, normal range: <50) | 75 (52–98) | 84 (57–111) | 77 (40–115) | 65 (8–120) | 116 (4–228) |
C-Reactive Protein (mg/l, normal range:<5) | 182 (145–219) | 178 (130–226) | 187 (90–284) | 178 (25–331) | 163 (74–225) |