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Table 3 Treatment regimens of study patients

From: Artesunate versus quinine in the treatment of severe imported malaria: comparative analysis of adverse events focussing on delayed haemolysis

Treatment regimen

All patients

Patients with delayed haemolysis,

 

n = 36

n = 5/16*

Quinine (iv) + Clindamycin (po)

9

0/4

Quinine (iv) + Doxycycline (po)

16

0/3

Quinine (iv) monotherapy

1

0/1

Quinine (iv) + Clindamycin (po) + Artesunate (ir)

1

1/1

Quinine (iv) + Doxycycline (po) + Artesunate (ir)

3

1/2

Quinine (iv) + Artesunate (ir)

1

0/1

Artesunate (iv) with subsequent Atovaquone/Proguanil (po)

4

2/3

Artesunate (iv) with subsequent Mefloquine (po)

1

1/1

  1. *a total of n = 16 contributed data for the primary endpoint assessment (delayed haemolysis).
  2. Abbreviation: iv intravenous, po orally, ir intrarectal.