Skip to main content

Table 5 Reported adverse events other than delayed haemolysis in patients treated with a primary regimen of quinine and of patients treated with a primary regimen of artesunate

From: Artesunate versus quinine in the treatment of severe imported malaria: comparative analysis of adverse events focussing on delayed haemolysis

Primary treatment

Quinine

Artesunate

 

n = 31

n = 5

Any adverse event

22 (71%)

3 (60%)

Hypoglycaemia (<50 mg/dl)

10 (32%)

0 (0%)

Hearing disturbances

12 (38%)

0 (0%)

Visual disturbances

1 (3%)

0 (0%)

Hepatotoxicity

1 (3%)*

0 (0%)

Prolongation of the QTc-interval (>500 ms)

3 (10%)

0 (0%)

Acute renal failure

8 (26%)

3 (60%)

Other**

2 (6%)

0 (0%)

  1. * treated with quinine and doxycycline.
  2. *** 1 patient with SIADH, 1 patient with clindamycin-induced eosinophilic pneumonitis.
  3. All p-values for between-group differences >0,05 by Fisher’s exact test.