Comparison of amino acid and nucleotide sequences of the Plasmodium vivax circumsporozoite CRR vk247. The sample code and the Gen Bank accession numbers are indicated at top of each repeat block and those from other isolates worldwide are within parenthesis. The amino acid residues are indicated by capital letters, and those corresponding to the nucleotide sequence are underlined; the amino acid substitutions are indicated underneath. On the left side the repeat units are numbered. Dots indicate absence of nucleotide variation. The non-synonymous nucleotide changes are indicated by upper-case letters. Sequences from isolates Mxch6 and PeruI are shown, which are identical to Iranian (AY632330.1) and Colombian (JN689931.1) isolates and different from sequences of Thailand and Brazilian isolates.