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Table 2 Prevalence of point mutation in dhfr and dhps gene in day 0 samples of patients enrolled for AS + SP therapeutic efficacy studies, central and eastern India, 2007 and 2010

From: A clinical and molecular study of artesunate + sulphadoxine-pyrimethamine in three districts of central and eastern India

  Keonjhar (n = 71) Ranchi (n = 53) WGH (n = 25)
Genes Codons n M %M n M % M n M %M
dhfr C59R 59 38 64 53 36 68 18 18 100
  S108N 60 60 100 50 50 100 19 19 100
  I164L 60 20 33 52 18 35 14 5 36
dhps K540E 28 11 39 28 4 12 10 6 60
  A581G 28 8 28 28 5 14 15 0 0
  1. Abbreviations: WGH, West Garo Hills; n, number; M, mutant.