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Table 4 Prevalence of dhfr / dhps haplotype in day 0 samples of patients enrolled for AS + SP therapeutic efficacy studies, central and eastern India, 2007 and 2010

From: A clinical and molecular study of artesunate + sulphadoxine-pyrimethamine in three districts of central and eastern India

Mutations Genotypes ( dhfr/ dhps) Keonjhar Ranchi WGH
   (n = 42) (n = 32) (n = 6)
   n % n % n %
4 N51R59N108I164/S436A437E540G581A613 - - 2 6 - -
4 N51R59N108L164/S436A437E540A581A613 2 4 - - 2 33
3 N51R59N108L164/ S436A437 K540A581A613 6 14 4 13 - -
3 N51R59N 108 I164/S436A437E540A581A613 4 10 2 6 3 50
3 N51C59N108L164/S436A437E540A581A613 1 2 - - - -
3 N51R59N108I164/S436A437K540G581A613 - - 2 6 - -
2 N51R59N108I164/S436A437K540A581A613 12 29 13 41 1 17
2 N51C59N108L164/S436A437K540A581A613 4 10 - - - -
2 N51C59N108I164/S436A437E540A581A613 4 10 - - - -
1 N51C59N108I164/S436A437K540A581A613 9 21 9 28 - -
  1. Abbreviations: WGH, West Garo Hills.
  2. Mutated amino acids are in bold.