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Table 4 Prevalence of dhfr / dhps haplotype in day 0 samples of patients enrolled for AS + SP therapeutic efficacy studies, central and eastern India, 2007 and 2010

From: A clinical and molecular study of artesunate + sulphadoxine-pyrimethamine in three districts of central and eastern India

Mutations

Genotypes ( dhfr/ dhps)

Keonjhar

Ranchi

WGH

  

(n = 42)

(n = 32)

(n = 6)

  

n

%

n

%

n

%

4

N51R59N108I164/S436A437E540G581A613

-

-

2

6

-

-

4

N51R59N108L164/S436A437E540A581A613

2

4

-

-

2

33

3

N51R59N108L164/ S436A437 K540A581A613

6

14

4

13

-

-

3

N51R59N 108 I164/S436A437E540A581A613

4

10

2

6

3

50

3

N51C59N108L164/S436A437E540A581A613

1

2

-

-

-

-

3

N51R59N108I164/S436A437K540G581A613

-

-

2

6

-

-

2

N51R59N108I164/S436A437K540A581A613

12

29

13

41

1

17

2

N51C59N108L164/S436A437K540A581A613

4

10

-

-

-

-

2

N51C59N108I164/S436A437E540A581A613

4

10

-

-

-

-

1

N51C59N108I164/S436A437K540A581A613

9

21

9

28

-

-

  1. Abbreviations: WGH, West Garo Hills.
  2. Mutated amino acids are in bold.