Treatment outcome | Day 28 | Day 42 | |||
---|---|---|---|---|---|
PP population, N (%) | ASAQ | AL | ASAQ | AL | % cured analysis |
N = 142 | N = 126 | N = 142 | N = 126 | ||
ACPR | 99 (69.7) | 108 (85.7) | 75 (52.8) | 71 (56.3) | Success |
ETF | 0 (0) | 1 (0.8) | 0 (0) | 1 (0.8) | Failure |
LCF or LPF | |||||
- P. falciparum recrudescence | 1 (0.7) | 2 (1.6) | 3 (2.1) | 5 (4.0) | Failure |
- P. falciparum re-infection | 39 (27.5) | 11 (8.7) | 61 (43.0) | 40 (31.7) | Excluded* |
- undetermined or missing PCR | 2 (1.4) | 2 (1.6) | 2 (1.4) | 5 (4.0) | Excluded* |
Non-P. falciparum malaria infection ** | 0 (0) | 2 (1.6) | 0 (0) | 4 (3.2) | Excluded |
No treatment outcome | |||||
- discontinued for SAE | 1 (0.7) | 0 (0) | 1 (0.7) | 0 (0) | Excluded |
Patients analysed | |||||
Genotyping-adjusted analysis | N = 100 | N = 111 | N = 78 | N = 77 | |
Genotyping-unadjusted analysis | N = 141 | N = 124 | N = 141 | N = 122 |