KM cure rate estimates | Observed proportion cured | |||
---|---|---|---|---|
mITT population | PP population | |||
Day 28 | ASAQ | AL | ASAQ | AL |
Genotyping-adjusted | ||||
% cured [95% CI] | 99.3 [95.1–99.9] | 97.9 [93.6–99.3] | 99.0 [94.6–100] | 97.3 [92.3–99.4] |
Genotyping-unadjusted | ||||
% cured [95% CI] | 71.2 [63.1– 77.9] | 87.5% [80.9–91.9] | 70.2 [61.9–77.6] | 87.1 [79.9–92.4] |
Day 42 | ||||
Genotyping-adjusted | ||||
% cured [95% CI] | 97.3 [91.6–99.1] | 94.2 [88.1–97.2] | 96.2 [89.2–99.2] | 92.2 [83.8–97.1] |
% difference # (UL 95% CI*) | −3.1 (1.2) | −3.9 (2.2) | ||
Genotyping-unadjusted | ||||
% cured [95% CI] | 52.7 [44.3–60.5] | 59.5 [50.9–67.1] | 53.2 [44.6–61.6] | 58. 2 [48.9–67.1] |