pfdhfr/ pfdhps allele | 2003 % | 2012 % | p- value [[20],[52]] |
|---|
51I/108N | 90[20] 84[52] | 100 |
0.
004/0.
001
|
59R
| 1[20] 0[52] | 1.7 | 0.477/1.000 |
436A
| 0[52] | 7.8 | 0.069 |
437G
| 89[20] 0[52] | 77.3 |
0.
013/0.
000
|
516F
| Â | 1.7* | Â |
K540
| 20[52] | 21.5 | 0.000 |
540E
| 79[20] | 76.9 | 0.860 |
540K/E | 80[52] | 1.5 |
0.
000
|
581G
| 14[20] 10[52] | 33.8 |
0.
001/0.
007
|
581A/G | 10[52] | 1.5 | 0.202 |
A613
| 100[20, 52] | 100 | 1.000 |
- p-values were calculated by comparing actual number of patients displaying each genotype from previous studies performed in Gedarif in 2003 [20, 52] and Gedarif and Kassala, 2006 [30]) and the current study (Kassala) by Fishers exact test. * not previously reported.
