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Table 1 Frequency distribution of pvdhfr-pvdhps haplotypes in P. vivax isolates from southern Pakistan

From: Prevalence of drug resistance associated mutations in Plasmodium vivax against sulphadoxine-pyrimethamine in southern Pakistan

pvdhfr-pvdhps haplotypes

Mutations

Karachi

Sindh

Baluchistan

Total (%)

IPFSTSI-AA

0

40 (40.8)

8 (40.0)

3 (23.1)

51 (38.9)

IPFSTN/T I-AA

1

17 (17.3)

3 (15.0)

4 (30.8)

24 (18.3)

IPFR TSI-AA

1

2 (2.04)

-

-

2 (1.53)

IPFSTSI-G A

1

7 (7.14)

2 (10.0)

-

9 (6.87)

IPFR TN/T I -AA

2

23 (23.5)

5 (25.0)

5 (38.5)

33 (25.2)

IPLR TSI-AA

2

2 (2.04)

1 (18.9)

-

3 (2.29)

IPFSTN/T I-G A

2

3 (3.06)

-

-

3 (2.29)

IPFR TN/T I-G A

3

1 (1.02)

-

-

1 (0.76)

IPFR TN/T I-GG

4

-

-

1 (7.7)

1 (0.76)

  1. pvdhfr: I13L ,P33L,F57L,S58R,T61M,S117N/T,I173L.
  2. pvdhps: A383G,A553G.
  3. Bold face represents change in amino acid.