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Table 3 Univariate and multivariate logistic regression of predictors for severe malaria

From: Severity of imported malaria: protective effect of taking malaria chemoprophylaxis

Variables Univariate analysis Multivariate analysis
   P-value Odds ratio (95% CI) P-value Odds ratio (95% CI)
Age   0.000 1.048 (1.024–1.071) 0.003 1.037 (1.013–1.062)
Sexe Male 0.256 0.726 (0.417–1.262) 0.181 0.661 (0.360–1.213)
Female 0.256 1.378 (0.792–2.398)   
Immunity Non-immune 0.000 3.944 (2.249–6.915)   
Partially or semi immune 0.860 0.950 (0.537–1.681)   
Reason for travel Tourist 0.196 1.464 (0.822–2.608)   
VFR 0.036 0.470 (0.233–0.950)   
Business 0.676 1.154 (0.590–2.258)   
Expat 0.175 1.903 (0.751–4.819)   
Sailor 0.050 2.195 (1.001–4.812)   
Other 0.450 0.570 (0.132–2.454)   
Region of acquisition Outside Africa 0.003 0.288 (0.128–0.647)   
North Africa 0.999 N.A.   
West Africa 0.000 3.567 (1.969–6.462) 0.000 3.287 (1.753–6.161)
Central Africa 0.142 0.409 (0.124–1.350)   
East Africa 0.356 0.639 (0.246–1.656)   
Southern Africa 0.543 1.984 (0.218–19.033)   
Season of infection March-August 0.362 0.780 (0.457–1.331)   
September-February 0.362 1.283 (0.751–2.190)   
Prophylaxis Adequate prophylaxis 0.006 0.137 (0.033–0.569) 0.007 0.132 (0.031–0.567)
Inadequate prophylaxis 0.257 0,639 (0.294–1.387) 0.143 0.540 (0.236–1.233)
No prophylaxis 0.001 3.235 (1.607–6.512)   
Duration of illness before diagnosis 1 to 7 days 0.670 0.882 (0.496–1.568)   
8 to 14 days 0.115 1.633 (0.887–3.005)   
15 to 28 days 0.478 0.644 (0.196–2.168)   
More than 28 days 0.478 0.644 (0.196–2.168)   
Combined variables Non-immune tourists 0.000 3.274 (1.770–6.058) 0.026 2.200 (1.101–4.396)
Partially-immune VFR 0.059 0.476 (0.221–1.029) 0.045 0.426 (0.185–0.981)
  1. Legend: Included n = 559, CI confidence interval, VFR visiting friends and relatives, N.A. not applicable.