Table 3 Univariate and multivariate logistic regression of predictors for severe malaria
From: Severity of imported malaria: protective effect of taking malaria chemoprophylaxis
Variables | Univariate analysis | Multivariate analysis | |||
|---|---|---|---|---|---|
| Â | Â | P-value | Odds ratio (95% CI) | P-value | Odds ratio (95% CI) |
Age |  | 0.000 | 1.048 (1.024–1.071) | 0.003 | 1.037 (1.013–1.062) |
Sexe | Male | 0.256 | 0.726 (0.417–1.262) | 0.181 | 0.661 (0.360–1.213) |
Female | 0.256 | 1.378 (0.792–2.398) |  |  | |
Immunity | Non-immune | 0.000 | 3.944 (2.249–6.915) |  |  |
Partially or semi immune | 0.860 | 0.950 (0.537–1.681) |  |  | |
Reason for travel | Tourist | 0.196 | 1.464 (0.822–2.608) |  |  |
VFR | 0.036 | 0.470 (0.233–0.950) |  |  | |
Business | 0.676 | 1.154 (0.590–2.258) |  |  | |
Expat | 0.175 | 1.903 (0.751–4.819) |  |  | |
Sailor | 0.050 | 2.195 (1.001–4.812) |  |  | |
Other | 0.450 | 0.570 (0.132–2.454) |  |  | |
Region of acquisition | Outside Africa | 0.003 | 0.288 (0.128–0.647) |  |  |
North Africa | 0.999 | N.A. | Â | Â | |
West Africa | 0.000 | 3.567 (1.969–6.462) | 0.000 | 3.287 (1.753–6.161) | |
Central Africa | 0.142 | 0.409 (0.124–1.350) |  |  | |
East Africa | 0.356 | 0.639 (0.246–1.656) |  |  | |
Southern Africa | 0.543 | 1.984 (0.218–19.033) |  |  | |
Season of infection | March-August | 0.362 | 0.780 (0.457–1.331) |  |  |
September-February | 0.362 | 1.283 (0.751–2.190) |  |  | |
Prophylaxis | Adequate prophylaxis | 0.006 | 0.137 (0.033–0.569) | 0.007 | 0.132 (0.031–0.567) |
Inadequate prophylaxis | 0.257 | 0,639 (0.294–1.387) | 0.143 | 0.540 (0.236–1.233) | |
No prophylaxis | 0.001 | 3.235 (1.607–6.512) |  |  | |
Duration of illness before diagnosis | 1 to 7 days | 0.670 | 0.882 (0.496–1.568) |  |  |
8 to 14 days | 0.115 | 1.633 (0.887–3.005) |  |  | |
15 to 28 days | 0.478 | 0.644 (0.196–2.168) |  |  | |
More than 28 days | 0.478 | 0.644 (0.196–2.168) |  |  | |
Combined variables | Non-immune tourists | 0.000 | 3.274 (1.770–6.058) | 0.026 | 2.200 (1.101–4.396) |
Partially-immune VFR | 0.059 | 0.476 (0.221–1.029) | 0.045 | 0.426 (0.185–0.981) | |