Skip to main content

Table 2 IC50 values of commonly used anti-malarial drugs in in vitro culture of Plasmodium falciparum and in Plasmodium vivax from Manaus, Amazonas State, Brazil

From: Use of a colorimetric (DELI) test for the evaluation of chemoresistance of Plasmodium falciparum and Plasmodium vivax to commonly used anti-plasmodial drugs in the Brazilian Amazon

  P. falciparum P. vivax
   IC50 (nM)   IC50 (nM)
Drug1 No. of isolates Geometric mean 95% CI2 Range No of isolates Geometric mean 95% CI2 Range
Chloroquine 64 361.8 266–492 9–3373 132 24.1 20–29 5–729
Quinine1 63 128.5 93–175 12–2174 - - - -
Mefloquine 66 14.2 10–20 2–723 78 18.1 14–23 2–337
Artesunate1 51 3.4 3–4 0.3–52 - -- -- -
  1. 1Performed only in P. falciparum cultures; 2CI, confidence interval.