Alignment and recombination at select MSP-3α regions. The less frequent variants are outlined in colour for seven regions of the amino acid MSP-3α alignment (positions of the region in the full 880 residue alignment are shown above sequence blocks). Dashes represent alignment gaps due to indel events. Haplotypes are represented to the right, with the presence of a deletion (unfilled gray squares), the more common allele (filled gray square), or the rarer allele (orange or blue) marked for each of the 7 polymorphic regions. 27 of the 48 P. vivax sequences are shown here.