Figure 7
Correlation between EPO and anti-EPO antibody at infection and recovery of all the semi-immune mice strains. Blood was harvested for serum at minimum Hb at infection and at recovery for EPO and anti-EPO antibody measurement as indicated in materials and methods. Number (n) of mice per strain at infection, Balb/c (n = 8), B6 (n = 7), CBA (n = 7) and NZW, (n = 6); and at recovery, Balb/c (n = 8), B6 (n = 8), CBA (n = 5) and NZW (n = 5)). Graph a. upper left is correlation for Balb/c; graph b. upper right is correlation for B6; graph c. lower left is correlation for CBA; graph d. is correlation for NZW. Continues line is the line of best fit, while r is Pearson coefficient. These are pooled data of two experiments. Log10 transformation of EPO was done on the EPO concentration of pg/ml after being converted from OD values from the ELISA readings. Anti-EPO antibody values (OD values) were also log10 transformed.