Brain oedema. A. Micrograph showing a representative case of highest brain oedema severity score. B. Effect of Azadirachta indica on the severity of brain oedema in Plasmodium berghei-infected (inf.) mice. Note the significant decrease in brain oedema severity following treatment with chloroquine (chlor.), artemether (artem.), or any of the doses of A. indica extract used. Data are mean ± SEM.