Culture-adapted Plasmodium falciparum isolates from UK travellers: in vitro drug sensitivity, clonality and drug resistance markers

Table 2 Multiplicity of infection in clinical isolates

Isolate	Sample	*pfmsp1*			*pfmsp2*		Minimum number of clones*
Isolate	Sample	K1	MAD20	RO33	FC27	IC	Per sample	Per isolate
HL1204 Kenya	Day 0 pre-treatment	0	1	2	0	1	3	4
	Day 1 post-treatment	0	2	2	0	1	4
	Culture-adapted	0	1	1	0	1	2
HL1205 Nigeria	Day 0 pre-treatment	1	0	1	3	1	4	5
	Day 1 post-treatment	2	0	1	4	1	5
	Culture-adapted	2	0	2	3	1	4
HL1209 South Sudan	Day 0 pre-treatment	0	2	2	4	2	6	6
	Day 1 post-treatment	0	1	2	4	2	6
	Culture-adapted	0	2	2	4	2	6
HL1210 Ghana	Day 0 pre-treatment	2	2	0	0	1	4	4
	Day 1 post-treatment	2	2	0	0	1	4
	Culture-adapted	2	2	0	0	1	4
HL1211 Ghana	Day 0 pre-treatment	2	0	0	0	3	3	6
	Day 1 post-treatment	2	0	0	0	3	3
	Culture-adapted	1	0	2	4	2	6
^†HL1212 Nigeria	Day 0 pre-treatment	3	2	1	2	1	6	6
^†HL1212 Nigeria	Culture-adapted	2	1	0	3	1	4	6
HL1214 Burkina Faso	Day 0 pre-treatment	0	1	1	0	2	2	2
	Day 1 post-treatment	0	0	0	0	0	0
	Culture-adapted	0	1	1	0	2	2

*The minimum number of clones in each sample was estimated by adding the highest number of bands for each Pfmsp allele.
^†No Day 1 post-treatment sample was obtained for HL1212.

ISSN: 1475-2875