Parasitaemia (A), survival rate (B), and clinical disease assessment by clinical score (C) in C57BL/6 mice infected with Schistosoma japonicum and then inoculated with 1×106Plasmodium berghei ANKA-pRBCs eight weeks later (co-infection) and were analysed together with P. berghei ANKA-mono-infected mice ( P. berghei ANKA). For monitoring the malaria parasitaemia, a Giemsa-stained thin smear was made daily. The open box indicates the susceptible period for CM. Values represent the means with SD (n=3 mice per group). Student t test by comparisons between the two groups was performed with * indicating P<0.01.