Figure 3

Mice in Plasmodium berghei ANKA-mono-infection group and Schistosoma japonicum-P. berghei ANKA-co-infection group were compared at different time points according to data obtained by flow cytometry. Proportion of splenic DCs subpopulation, CD11c⁺CD11b⁺ and CD11c⁺CD45R⁄ B220⁺, were analysed in A and B, with absolute number of these DCs present in C and D. Proportion of splenic CD11c⁺ DCs expressing TLR4 , TLR9, MHC class II, and CD86 of the two groups were compared in E, F, G, H, respectively. MFI of TLR4, TLR9, MHC class II, and CD86, which were expressed on CD11c⁺CD11b⁺ DCs and CD11c⁺CD45R⁄ B220⁺ DCs were present in I and J. At each time point, at least three mice per group were sacrificed. Bars represent the mean values ± SD. Student t test by comparisons between the two groups was performed with * indicating P<0.05 and # indicating P<0.01.