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Table 3 CSP repetitive motifs and the polymorphism found in all Laverania species analyzed

From: Malarial parasite diversity in chimpanzees: the value of comparative approaches to ascertain the evolution of Plasmodium falciparum antigens

Species

NCBI No.

Repeat motifs

Ï€

dS-dN (SE) / p (ZTest)

Repeat motif combination

P. billcollinsi

JX899657

R1: [DDANN]3

0.040 (0.039)

−0.050 (0.049) 0.248 (1.161) dS = dN

Pf1-[1]3[2]3--Pf2--[3]24[3]44[3]34[3]55[3]35-PN

R2: [DNANN]3

R3: [PNANPN]17

0.078 (0.045)

0.470 ± 0.224 0.017 (−2.431) dS > dN

R4: [PNAD]3

  

R5: [PNANPNPN]2

  

P. billbrayi

JX899659

R4: [PNAD]4

0.104 (0.053)

0.315 ± 0.203 0.023 (−2.298) dS > dN

Pf2---4[6]24[6]64[6]64[6]15-PN

R6: [PNAN]29

P. gaboni

JX899661

R4: [PNAD]2

0.128 (0.058)

0.347 ± 0.246 0.021 (−2.338) dS > dN

Pf2---[6]27[6]27[6]24[6]74[6]13-PN

R6: [PNAN]26

R7: [PNVD]2

P. reichenowi

 

R6: [PNAN]26

0.164 (0.063)

0.211 ± 0.231 0.014 (−2.503) dS > dN

Pf2---[(6-7)]46867[(6-8)]3[6]17-PN

R7: [PNVD]5

R8: [PNVN]4

Plasmodium sp. (isolate Shegue)

JX899658

R6: [PNAN]27

Pf2---[(6-7)]46867[(6-8)]5[6]16-PN

R7: [PNVD]5

R8: [PNVN]6

Plasmodium sp. (isolate 20)

JX899660

R6: [PNAN]26

Pf2---[(7-6)]47[6]27[(6-8)]2[6]18-PN

R7: [PNVD]6

R8: [PNVN]2

P. falciparum (isolate 14)

JX899664

R6: [PNAN]36

0.131 (0.047)

0.224 ± 0.149 0.002 (−3.093) dS > dN

Pf2---[(6-7)]3[6]117[6]22-PN

R7: [PNVD]4

P. falciparum (isolate 22)

JX899662

R6: [PNAN]37

Pf2---[(6-7)]3[6]157[6]19-PN

R7: [PNVD]4

P. falciparum (isolate 30)

JX899663

R6: [PNAN]37

Pf2---[(6-7)]3[6]157[6]19-PN

R7: [PNVD]4

P. falciparum(isolate 3D7)

 

R6: [PNAN]40

Pf2---[(6-7)]3[6]197[6]18-PN

R7: [PNVD]4

  1. PN are amino acids located at the end of the repetitive region. Pf1 and Pf2 are peptides described by Ancsin and Kisilevsky 2004[63].