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Table 4 Polymorphism found in var2CSA DBL1 gene sequences from P. falciparum and chimpanzee malarial parasites

From: Malarial parasite diversity in chimpanzees: the value of comparative approaches to ascertain the evolution of Plasmodium falciparum antigens

 

VAR2CSA-DBL1

Species

π (SD.)

Ds

Dn

Ds-Dn (SD.)

p (Z-stat)

P. falciparum (Human, N = 21)

0.1173 (0.0064)

0.1674

0.1200

0.0471 (0.0186)

0.0227 (−2.3078) Ds > Dn

P. falciparum (Human-Chimp, N = 24)

0.1146 (0.0066)

0.1641

0.1171

0.0470 (0.0209)

0.0207 (−2.3449) Ds > Dn

Chimpanzee malaria (all Chimp, N = 8)

0.0939 (0.0062)

0.1424

0.0914

0.0509 (0.0206)

0.0087 (−2.6660) Ds > Dn

Chimpanzee malaria (Chimp-Clade A, N = 2)

0.0122 (0.0035)

0.0360

0.0069

0.0291 (0.0145)

0.0464 (−2.0124) Ds > Dn

Chimpanzee malaria (Chimp-Clade B, N = 6)

0.0895 (0.0065)

0.1240

0.0893

0.0347 (0.0188)

0.0797 (−1.7670) Ds = Dn

  1. Clade A and B are shown in Figure 9.