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Table 2 Unadjusted and adjusted 1 relative risk of positive RDT result among family and neighbours of index cases across residence, sex, age, occupation, recent travel history, and bed net use

From: Case investigation and reactive case detection for malaria elimination in northern Senegal

 

N

RDT-positive

Unadjusted RR

Adjusted RR1

n (%)

(95% CI)

(95% CI)

Residence – compound

Index case

1,076

14

(1.3)

6.42 (2.79-14.80)***

3.18 (1.21-8.39)*

Neighbouring

4,444

9

(0.2)

ref

ref

Sex

     

Male

2,735

17

(0.6)

2.88 (1.14-7.29)*

1.58 (0.55-4.52)

Female

2,779

6

(0.2)

ref

ref

Age

     

0-4

1,011

1

(0.1)

ref

--

5-14

1,468

6

(0.4)

4.13 (0.50-34.28)

--

15-24

1,151

6

(0.5)

5.27 (0.64-43.71)

--

25-49

1,336

8

(0.6)

6.05 (0.76-48.33)

--

50+

511

1

(0.2)

1.98 (0.12-31.57)

--

Occupation among people age 15+

Not employed outside of the home

1,019

2

(0.2)

ref

--

Student

518

4

(0.8)

3.93 (0.72-21.40)

--

Agriculture and/or animal husbandry

186

0

(0.0)

0.0

--

Unskilled labourer

209

2

(1.0)

4.87 (0.69-34.41)

--

Skilled labourer

191

1

(0.5)

2.67 (0.24-29.27)

--

Skilled professional

74

0

(0.0)

0.0

--

Merchant

286

3

(1.1)

5.34 (0.90-31.82)

--

Other

123

1

(0.8)

4.14 (0.38-45.35)

--

Travel within the previous 15 days

Any travel

83

13

(15.7)

85.16 (38.44-188.67)***

---

No travel

5,437

10

(0.2)

ref

---

Travel within Saint-Louis region (home region)

32

1

(3.1)

7.80 (1.08-56.10)*

9.57 (2.32-39.45)**

None within the region

5,488

22

(0.4)

ref

ref

Travel within Dakar region

19

2

(10.5)

27.57 (6.95-109.47)***

19.93 (4.02-98.83)***

None within the region

5,501

21

(0.4)

ref

ref

Travel within other region in Senegal

30

10

(33.3)

140.77 (67.01-295.72)***

94.30 (34.24-259.69)***

None within other regions

5,490

13

(0.2)

ref

ref

Travel to neighbouring countries

3

1

(33.3)

83.59 (15.99-436.96)***

omitted

None to neighbouring countries

5,517

22

(0.4)

ref

---

Bed net use the previous night

No

387

5

(1.3)

3.64 (1.36-9.76)*

1.90 (0.58-6.18)

Yes

5,077

18

(0.4)

ref

ref

Total

5,5202

23

(0.4)

--

--

  1. *p < 0.05, **p < 0.01, ***p < 0.001.
  2. 1 Full model (observations = 5,458) containing residence, sex, recent travel, and bed net use. Travel to neighbouring countries was omitted due to instability with small n (n = 3 with travel history to neighbouring countries).
  3. 2 Missing data: Sex, n = 6; Age, n = 43; Occupation among people age 15+, n = 392; Bed net use, n = 60.