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Table 1 Anti-plasmodial activity data

From: Cytostatic versus cytocidal profiling of quinoline drug combinations via modified fixed-ratio isobologram analysis

  Experimental IC50a(nM) Experimental LD50a(nM)
Drug HB3 Dd2 Rfb HB3 Dd2 Rfb
CQ 23.8 (0.7) 212.3 (9.0) 9.0 120.0 (10.0) 15300.0 (900.0) 127.5
AQ 10.1 (0.6) 26.5 (0.4) 2.6 37.2 (1.2) 52.4 (2.3) 1.4
PQ 1990.0 (16.6) 4695.0 (62.1) 2.4 8640.0 (50.0) 2810.0 (10.0) 0.3
TQ 2189.9 (18.7) 2092.2 (20.0) 1.0 42700.0 (2042.6) 12100.0 (706.0) 0.3
MB 5.3 (0.09) 5.5 (0.07) 1.0 120.2 (9.5) 108.0 (6.6) 0.9
  1. aAverage of 3 independent measurements, each performed in triplicate (9 determinations total), with S.E.M. reported in parentheses.
  2. bResistance factor (Rf) = Dd2 value/HB3 value.